09:20Opening Remarks

Shuh Narumiya   Kyoto University, Japan

Session 1 -Part 1-

General Introduction : Towards Human Biology

Chairpersons: Akira Sawa & Anissa Abi-Dargham

09:25S1-1　The Contribution of Genes and Environment to the Evolution of Psychosis

Raquel E. Gur

University of Pennsylvania, U. S. A.

09:55S1-2　An integrated view of Complex psychiatric phenotypes

Shigenobu Kanba

Kyushu University, Japan

Coffee Break (15 min.) 10:25-10:40

Session 1 -Part 2-

10:40S1-3　Charting mental disorders from childhood to midlife

Avshalom Caspi

Duke University, U. S. A.

11:10S1-4　Evidence synthesis: Present and future

Toshiaki A. Furukawa

Kyoto University, Japan

＜Lunch＞ 11:40-12:20 (40 min.)

＜Poster Session＞ (45 min. each)
12:20-13:05 / Odd Number
13:05-13:50 / Even Number

Session 2

Imaging & Computation

Chairpersons: Shigenobu Kanba & Raquel E. Gur

13:55S2-1　New insights into the topography and mechanisms of dopaminergic alterations in schizophrenia

Anissa Abi-Dargham

Stony Brook University, U. S. A.

14:25S2-2　Biological factors related to the onset of psychosis

Philip McGuire

King’s College London, U. K.

14:55S2-3　E/I-balance and gamma-band oscillations across
illness-stages in Schizophrenia: Using Magnetoencephalography to identify circuit dysfunctions and biomarkers

Peter J. Uhlhaas

Charite Universitätsmedizin Berlin, Germany

15:25S2-4　Salience account of delusion and hallucination

Jun Miyata

Kyoto University, Japan

Coffee Break (25 min.) 15:55-16:20

Session 3

Synaptic / Neural Circuit Mechanisms

Chairpersons: Tomoyuki Furuyashiki & Jonathan Kipnis

16:20S3-1　Computational neuroscience approach to mental disorders

Mitsuo Kawato

Advanced Telecommunications Research Institute International (ATR), Japan

16:50S3-2　Multi-scale Understanding of Synaptic Pathology of Psychiatric Disorders

Akiko Hayashi-Takagi

RIKEN Center for Brain Science, Japan

17:20S3-3　Neural Circuit Mechanisms of Emotional and Social Processing

Kay M. Tye

The Salk Institute for Biological Studies, U. S. A.

17:50S3-4　Innate fear odors elicit a physiological crisis mode that promotes survival in life-threatening situations

Ko Kobayakawa

Kansai Medical University, Japan

Welcome Reception 18:35-20:20

Session 4

Inflammation & Mental Illness

Chairpersons: Akiko Hayashi-Takagi & John H. Krystal

09:00S4-1　Meningeal immunity and lymphatics in CNS function and dysfunction

Jonathan Kipnis

University of Virginia, U. S. A.

09:30S4-2　Psychological Stress and Prolonged Anxiety: Key interactions between Microglia, Monocytes, and Endothelial cells

Jonathan Godbout

The Ohio State University, U. S. A.

10:00S4-3　Stress and innate immune responses in the brain

Tomoyuki Furuyashiki

Kobe University, Japan

10:30S4-4　Inflammation and depression

Edward T. Bullmore

University of Cambridge, U. K.

Coffee Break (25 min.) 11:00-11:25

Session 5

Disease Trajectory

Chairperson: Avshalom Caspi

11:25S5-1　Looking for critical mediators in major mental illnesses: early detection and intervention

Akira Sawa

Johns Hopkins Hospital, U. S. A.

11:55S5-2　Next Generation Therapeutics of Anxiety and PTSD: neural circuitry & cell-type specific approaches to amygdala functioning and threat processing

Kerry J. Ressler

McLean Hospital, U. S. A.

＜Speaker's Photo Session＞ 12:25-12:35 (10 min.)

＜Lunch＞12:35-13:20 (45 min.)

＜Poster Session -Free Discussion-＞13:20-14:05 (45 min.)

Session 6 -Part 1-

Translation

Chairpersons: Shuh Narumiya & Edward T. Bullmore

14:05S6-1　Rapid-Acting Antidepressants: New treatments, new hope, and new insights into the brain

John H. Krystal

Yale University school of Medicine, U. S. A.

14:35S6-2　Quo Vadis Ketamine Enantiomers?

Kenji Hashimoto

Chiba University, Japan

Coffee Break (20 min.) 15:05-15:25

Session 6 -Part 2-

15:25S6-3　Prefrontal cortical synaptic remodeling in depression-related behavioral states

Conor Liston

Weill Cornell Medicine, U. S. A.

15:55S6-4　Development and Stress: Exploring Novel Drugs Targeting Inflamed Brain for Psychiatric Disorders

Atsushi Kamiya

Johns Hopkins University, U. S. A.

16:25S6-5　Modeling Neuropsychiatric Disorders using Human Stem Cells

Fred H. Gage

The Salk Institute for Biological Studies, U. S. A.

16:55Award Ceremony

Kay M. Tye  The Salk Institute for Biological Studies, U. S. A.
Raquel E. Gur  University of Pennsylvania, U. S. A.

17:05Closing Remarks

Akira Sawa  Johns Hopkins Hospital, U. S. A.