The 12th Takeda Science Foundation Symposium on PharmaSciences

Program

as of December 3, 2025

Day 1 (January 23, 2026)

Opening Remarks &Keynote

9:00Opening Remarks

Takanori Takebe

Takanori Takebe Cincinnati Children’s/ Institute of Science Tokyo/ The University of Osaka USA/Japan

9:10Keynote

Archaic Genomics

Svante Pääbo

Svante Pääbo Max Planck Institute Germany

【S1: Development 1】Chairperson: Sergiu Pasca

9:35S1-1

Mechanism and in vitro reconstitution of human germ-cell development

Mitinori Saitou

Mitinori Saitou Kyoto University Japan

10:00S1-2

Using organoids to understand and target the human brain

Madeline A. Lancaster

Madeline A. Lancaster MRC Laboratory of Molecular Biology UK

10:25S1-3

Developmental Self-Organization Principles Enable Organoid Modeling of Periodic Cartilage Patterning

Mitsuru Morimoto

Mitsuru Morimoto RIKEN Center for Biosystems Dynamics Research Japan

Coffee Break (20 min.) 10:50-11:10

【S1: Development 2】Chairperson: Juan Carlos Belmonte

11:10S1-4

Towards reconstituting human and primate embryonic development in vitro

Cantas Alev

Cantas Alev Kyoto University Japan

11:35S1-5

Organoids to model maternal-fetal interactions in human pregnancy

Margherita Yayoi Turco

Margherita Yayoi Turco Friedrich Miescher Institute for Biomedical Research Switzerland

12:00S1-6

Decoding the Logic of Self-Organization in Embryos and Their Stem Cell Models

xxxxx

Magdalena Zernicka-Goetz California Institute of Technology USA

Speakers‘ Photo Session (10 min.) 12:25-12:35
Lunch & Poster Session: <Lunch > 12:35-13:35 (60 min.)
<Poster Session> 13:35-14:30 / Odd Number(55 min.), 14:30-15:25 / Even Number (55 min)
Break (5 min.) 15:25-15:30

【S2: Disease 1】Chairperson: James M Wells

15:30S2-1

Organoids for cystic fibrosis precision medicine

Jeffrey Beekman

Jeffrey Beekman UMC Utrecht Netherlands

15:55S2-2

Culturing Human Epithelial Organoids in 3D and 2D

Hans Clevers

Hans Clevers Utrecht University Netherlands

16:20S2-3

Lung organoids: windows to mechanism and therapy of lung disease and cancer

Carla Kim

Carla Kim Boston Children’s Hospital USA

Coffee Break (20 min.) 16:45-17:05

【S2: Disease 2】Chairperson: Margherita Yayoi Turco

17:05S2-4

Understanding of human disease biology using organoids

Toshiro Sato

Toshiro Sato Keio University Japan

17:30S2-5

Moving from an understanding of kidney development to new therapies

Melissa Little

Melissa Little Murdoch Children's Research Institute Australia

Welcome Reception (90 min.) 18:10-19:40

Day 2 (January 24, 2026)

【S3: Diversity 1】Chairperson: Juergen Knoblich

9:00S3-1

Human brain organoids record the passage of time over multiple years in culture

Paola Arlotta

Paola Arlotta Harvard University USA

9:25S3-2

Engineering tissue complexity into human PSC-derived gastrointestinal organoids

James M. Wells

James M. Wells Cincinnati Children’s USA

9:50S3-3

How breast tissue architecture and the menstrual cycle control tumor initiation and chemotherapy sensitivity

Jacco van Rheenen

Jacco van Rheenen Netherlands Cancer Institute Netherlands

Coffee Break (20 min.) 10:15-10:35

【S3: Diversity 2】Chairperson: Paola Arlotta

10:35S3-4

Cardioids unravel human heart development and disease

Sasha Mendjan

Sasha Mendjan Institute of Molecular Biotechnology Austria

11:00S3-5

Human Pluripotent Stem Cells, Organoids, Disease Modeling and Drug Screening

Shuibing Chen

Shuibing Chen Weill Cornell Medicine USA

11:25S3-6

Engineering Hepato-Biliary-Pancreatic Organogenesis from Pluripotency

Takanori Takebe

Takanori Takebe Cincinnati Children’s/ Institute of Science Tokyo/ The University of Osaka USA/Japan

Lunch & Poster Session: <Lunch > 11:50-12:45 (55 min.)
<Poster Session -Free Discussion-> 12:45-13:40 (55 min.)

【S4: Discovery 1】Chairperson: Hans Clevers

13:40S4-1

Design principles of tissue organization

Prisca Liberali

Prisca Liberali Friedrich Miescher Institute for Biomedical Research Switzerland

14:05S4-2

Engineering next-generation tumor organoids

Matthias P. Lütolf

Matthias P. Lütolf Institute of Human Biology/Swiss Federal Institute of Technology Lausanne Switzerland

Coffee Break (20 min.) 14:30-14:50

【S4: Discovery 2 & Closing Keynote】Chairperson:Melissa Little

14:50S4-3

Spatiotemporal dynamics of sperm production in the mouse testis

Benjamin Simons

Benjamin Simons University of Cambridge UK

15:15Closing Keynote

A Decade of Molecular Cell Atlases

Steve Quake

Steve Quake Stanford University USA

Award Ceremony & Closing Remarks (20 min.) 15:40-16:00